Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_01450COG2086 Electron transfer flavoprotein, beta subunit. (252 aa)    
Predicted Functional Partners:
ISM_01455
COG2025 Electron transfer flavoprotein, alpha subunit.
 0.999
ISM_13185
Electrotransfer ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone.
 
 0.999
ISM_06020
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.961
ISM_12240
Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.961
ISM_12680
COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.961
ISM_04010
Putative glycolate oxidase; COG0277 FAD/FMN-containing dehydrogenases.
  
 0.945
ISM_07825
Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.906
ISM_12595
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.906
nuoI
NADH dehydrogenase I, I subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 0.898
ISM_04820
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
  
 0.879
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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