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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_01485Low molecular weight phosphotyrosine protein phosphatase; COG0394 Protein-tyrosine-phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (158 aa)    
Predicted Functional Partners:
ISM_10720
Hypothetical protein; COG0491 Zn-dependent hydrolases, including glyoxylases.
   
 
 0.908
ISM_07410
COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis.
  
 
 0.764
ISM_06815
Thioredoxin; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family.
  
 
 0.735
ISM_07435
COG3118 Thioredoxin domain-containing protein.
  
 
 0.735
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
 
     0.724
ybeY
Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.694
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
   
   0.680
rsmH
S-adenosyl-methyltransferase MraW; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
    
   0.678
infB-2
Translation initiation factor; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.
    
   0.678
ISM_12175
COG0415 Deoxyribodipyrimidine photolyase; Belongs to the DNA photolyase family.
    
   0.678
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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