Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02080COG1764 Predicted redox protein, regulator of disulfide bond formation. (158 aa)    
Predicted Functional Partners:
ISM_02085
COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.
       0.778
ISM_02090
Magnesium transporter; Acts as a magnesium transporter.
       0.778
ISM_07425
Putative two-component system sensor histidine kinase; COG2203 FOG: GAF domain.
   
    0.722
ISM_09556
COG3237 Uncharacterized protein conserved in bacteria; Belongs to the UPF0337 (CsbD) family.
  
  
 0.641
ISM_07130
Proteinase; COG0693 Putative intracellular protease/amidase.
  
  
 0.578
ISM_16365
Lipoprotein, SmpA/OmlA family protein; COG2913 Small protein A (tmRNA-binding).
   
  
 0.538
ISM_02095
COG2340 Uncharacterized protein with SCP/PR1 domains.
       0.473
ISM_01555
Hypothetical protein.
   
  
 0.456
ISM_09366
Possible peptidoglycan binding protein; COG1652 Uncharacterized protein containing LysM domain.
  
    0.420
ISM_02105
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
 
     0.411
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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