| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02095 | ISM_02100 | ISM_02095 | ISM_02100 | COG2340 Uncharacterized protein with SCP/PR1 domains. | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.660 |
| ISM_02100 | ISM_02095 | ISM_02100 | ISM_02095 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | COG2340 Uncharacterized protein with SCP/PR1 domains. | 0.660 |
| ISM_02100 | ISM_06430 | ISM_02100 | ISM_06430 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.670 |
| ISM_02100 | cysC | ISM_02100 | ISM_11065 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.682 |
| ISM_02100 | cysQ | ISM_02100 | ISM_07035 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.791 |
| ISM_02100 | nusA | ISM_02100 | ISM_06530 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.707 |
| ISM_02100 | nusB | ISM_02100 | ISM_00110 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Putative N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.665 |
| ISM_02100 | nusG | ISM_02100 | ISM_01920 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.710 |
| ISM_02100 | rpoB | ISM_02100 | ISM_01895 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.674 |
| ISM_02100 | rpoC | ISM_02100 | ISM_01890 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.701 |
| ISM_02100 | rpoZ | ISM_02100 | ISM_13780 | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.729 |
| ISM_06430 | ISM_02100 | ISM_06430 | ISM_02100 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.670 |
| ISM_06430 | cysC | ISM_06430 | ISM_11065 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.509 |
| ISM_06430 | cysQ | ISM_06430 | ISM_07035 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.569 |
| ISM_06430 | nusA | ISM_06430 | ISM_06530 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.919 |
| ISM_06430 | nusG | ISM_06430 | ISM_01920 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.710 |
| ISM_06430 | rpoB | ISM_06430 | ISM_01895 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.924 |
| ISM_06430 | rpoC | ISM_06430 | ISM_01890 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.960 |
| ISM_06430 | rpoZ | ISM_06430 | ISM_13780 | Ribosomal RNA small subunit methyltransferase B, putative; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | DNA-directed RNA polymerase omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.864 |
| cysC | ISM_02100 | ISM_11065 | ISM_02100 | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family. | 0.682 |