Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02105DNA-binding protein, putative; COG1396 Predicted transcriptional regulators. (99 aa)    
Predicted Functional Partners:
ISM_11810
HAD-superfamily subfamily IIA hydrolase; COG0647 Predicted sugar phosphatases of the HAD superfamily.
  
  
  0.722
ISM_09045
Hypothetical protein.
  
     0.683
ISM_06525
Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.
 
     0.679
ISM_11710
Hypothetical protein; COG0500 SAM-dependent methyltransferases.
  
     0.664
ISM_12070
COG3820 Uncharacterized protein conserved in bacteria.
  
     0.661
ISM_02100
Inositol monophosphatase family protein; COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family.
       0.653
ISM_06870
HD domain protein; COG1896 Predicted hydrolases of HD superfamily.
  
     0.645
ISM_09050
Hypothetical protein.
  
     0.637
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
  
    0.619
ISM_01290
COG4765 Uncharacterized protein conserved in bacteria.
  
     0.597
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.