STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02110Oxidoreductase, zinc-binding dehydrogenase family protein; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (295 aa)    
Predicted Functional Partners:
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
 
 0.965
ISM_03940
Dihydrolipoamide acetyltransferase; COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes.
   
 0.711
ISM_02075
AMP-binding protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
 0.700
ISM_15690
Benzoate-coenzyme A ligase, putative; COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases.
 
 
 0.666
ISM_16725
COG2977 Phosphopantetheinyl transferase component of siderophore synthetase; Belongs to the P-Pant transferase superfamily.
    
  0.657
ISM_05120
COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
 
 0.640
ISM_05030
Hypothetical protein; COG2030 Acyl dehydratase.
 
 0.611
ISM_02060
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
 
 0.595
ISM_03020
AMP-ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
   
 0.590
ISM_04335
malonyl-CoA synthase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
   
 0.590
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.