STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02160Metallo-beta-lactamase family protein; COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; Belongs to the UPF0173 family. (230 aa)    
Predicted Functional Partners:
gatC
glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family.
       0.617
gatA
glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
     
 0.599
ISM_02140
N-acetylmuramoyl-L-alanine amidase, family 2; COG3023 Negative regulator of beta-lactamase expression.
       0.506
ISM_02145
Hypothetical protein.
       0.506
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
     
 0.469
ISM_11490
COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family.
     
 0.428
ISM_11470
COG3853 Uncharacterized protein involved in tellurite resistance; Belongs to the TelA family.
      
 0.422
ISM_11475
Hypothetical protein.
      
 0.422
ISM_06995
PTS IIA-like nitrogen-regulatory protein PtsN; COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type).
    
 0.412
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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