Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_02285Mechanosensitive ion channel family protein; COG3264 Small-conductance mechanosensitive channel. (438 aa)    
Predicted Functional Partners:
ISM_02290
COG2081 Predicted flavoproteins.
       0.782
ISM_11140
Hypothetical protein; COG0840 Methyl-accepting chemotaxis protein.
  
     0.741
ISM_02295
Hypothetical protein.
       0.559
ISM_17100
Membrane protein, MarC family protein; COG2095 Multiple antibiotic transporter.
  
    0.553
ISM_16175
COG0776 Bacterial nucleoid DNA-binding protein.
  
     0.537
ISM_02280
Hypothetical protein; COG1403 Restriction endonuclease.
       0.534
ISM_17225
Glutathione-regulated potassium-efflux system protein; COG0475 Kef-type K+ transport systems, membrane components.
     
 0.488
ISM_16525
Lipoprotein, putative.
  
     0.415
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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