Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02320Glutathione-dependent formaldehyde dehydrogenase; COG1062 Zn-dependent alcohol dehydrogenases, class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (370 aa)    
Predicted Functional Partners:
ISM_08725
S-formylglutathione hydrolase, putative; Serine hydrolase involved in the detoxification of formaldehyde.
 0.999
ISM_11415
Hypothetical protein; COG1454 Alcohol dehydrogenase, class IV.
    
 0.859
ISM_06035
Alkane-1 monooxygenase, putative.
     
 0.773
ISM_07285
Fatty acid desaturase family protein.
     
 0.773
ISM_09180
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 0.755
ISM_12055
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 0.755
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
  
 
  0.705
ISM_08590
ephB, putative; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
    
  0.646
ISM_02315
Hypothetical protein; COG0625 Glutathione S-transferase.
 
  
 0.624
dusA
tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily.
    
   0.585
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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