Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02350Cytosol aminopeptidase family protein; COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family. (466 aa)    
Predicted Functional Partners:
ISM_00300
COG0308 Aminopeptidase N.
  
 0.901
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
  
  
 
0.884
gshB
COG0189 Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase); Belongs to the prokaryotic GSH synthase family.
   
 
 0.883
ISM_10156
Gamma-glutamyltranspeptidase, putative; COG0405 Gamma-glutamyltransferase.
  
  
 0.881
ISM_02470
Cation transport protein ChaC, putative; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
  0.850
ISM_05945
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.850
ISM_02345
NLP/P60 family protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
       0.845
ISM_08755
COG1448 Aspartate/tyrosine/aromatic aminotransferase.
   
 0.822
ISM_14460
Gamma-glutamyltranspeptidase; COG0405 Gamma-glutamyltransferase.
     
 0.786
ISM_02340
Agmatinase; COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Belongs to the arginase family.
     
 0.783
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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