STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02360Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (216 aa)    
Predicted Functional Partners:
ISM_07260
Bacterial transferase family protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.
    
 0.932
ISM_09130
Hypothetical protein; COG0110 Acetyltransferase (isoleucine patch superfamily).
    
 0.932
ISM_15580
Predicted ferripyochelin binding protein; COG0663 Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily.
    
 0.932
ISM_02355
Hypothetical protein.
 
     0.720
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
  
 0.700
ISM_01410
COG0659 Sulfate permease and related transporters (MFS superfamily).
 
 
 0.668
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 
 0.570
ISM_02350
Cytosol aminopeptidase family protein; COG0260 Leucyl aminopeptidase; Belongs to the peptidase M17 family.
       0.535
ISM_02345
NLP/P60 family protein; COG0791 Cell wall-associated hydrolases (invasion-associated proteins).
       0.533
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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