Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02380COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (312 aa)    
Predicted Functional Partners:
ISM_02375
Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily.
       0.773
ISM_04860
WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat.
   
 0.771
ISM_07585
Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
    
 0.757
ISM_00035
Hypothetical protein; COG0457 FOG: TPR repeat.
    
 0.726
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 0.711
ISM_11250
Hypothetical protein; COG0464 ATPases of the AAA+ class.
    
 0.693
ISM_17790
COG0464 ATPases of the AAA+ class.
    
 0.693
ISM_10091
Trypsin; COG5640 Secreted trypsin-like serine protease.
    
  0.680
ISM_09411
Hypothetical protein.
    
   0.674
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
   0.666
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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