STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02380COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. (312 aa)    
Predicted Functional Partners:
ISM_04860
WD domain/cytochrome c family protein; COG2319 FOG: WD40 repeat.
    
 0.893
ISM_07585
Helicase; COG0553 Superfamily II DNA/RNA helicases, SNF2 family.
    
 0.868
ISM_02375
Membrane protein, putative; COG0477 Permeases of the major facilitator superfamily.
       0.773
ISM_11250
Hypothetical protein; COG0464 ATPases of the AAA+ class.
    
 0.734
ISM_17790
COG0464 ATPases of the AAA+ class.
    
 0.734
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
 
 
 0.719
ISM_10526
COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.677
ISM_07610
Hypothetical protein; COG1196 Chromosome segregation ATPases.
    
 0.674
smc
SMC protein; Required for chromosome condensation and partitioning. Belongs to the SMC family.
    
 0.674
cobB
COG0846 NAD-dependent protein deacetylases, SIR2 family; Belongs to the sirtuin family. Class III subfamily.
    
 
 0.671
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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