| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_02425 | ISM_02430 | Hypothetical protein; COG0504 CTP synthase (UTP-ammonia lyase). | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | 0.574 |
| ISM_02430 | ISM_02425 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Hypothetical protein; COG0504 CTP synthase (UTP-ammonia lyase). | 0.574 |
| ISM_02430 | ISM_04420 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Selenium-binding protein, putative. | 0.450 |
| ISM_02430 | ISM_05230 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. | 0.438 |
| ISM_02430 | ISM_06475 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | COG3453 Uncharacterized protein conserved in bacteria. | 0.641 |
| ISM_02430 | ISM_08180 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.632 |
| ISM_02430 | ISM_08760 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | 0.468 |
| ISM_02430 | ISM_12435 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase. | 0.650 |
| ISM_02430 | ISM_12615 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | CobG; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.457 |
| ISM_02430 | ISM_15735 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.457 |
| ISM_02430 | ISM_15740 | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.448 |
| ISM_04420 | ISM_02430 | Selenium-binding protein, putative. | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | 0.450 |
| ISM_04420 | ISM_06475 | Selenium-binding protein, putative. | COG3453 Uncharacterized protein conserved in bacteria. | 0.643 |
| ISM_04420 | ISM_08760 | Selenium-binding protein, putative. | Thiosulfate sulfurtransferase, putative; COG2897 Rhodanese-related sulfurtransferase. | 0.744 |
| ISM_04420 | ISM_12615 | Selenium-binding protein, putative. | CobG; COG0155 Sulfite reductase, beta subunit (hemoprotein); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.422 |
| ISM_04420 | ISM_15735 | Selenium-binding protein, putative. | COG0155 Sulfite reductase, beta subunit (hemoprotein). | 0.739 |
| ISM_05230 | ISM_02430 | Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | 0.438 |
| ISM_05230 | ISM_08180 | Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.479 |
| ISM_05230 | ISM_12435 | Hypothetical protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases. | Hypothetical protein; COG0607 Rhodanese-related sulfurtransferase. | 0.603 |
| ISM_06475 | ISM_02430 | COG3453 Uncharacterized protein conserved in bacteria. | Membrane protein, putative; COG3182 Uncharacterized iron-regulated membrane protein. | 0.641 |