Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02625Hypothetical protein; COG3232 5-carboxymethyl-2-hydroxymuconate isomerase. (113 aa)    
Predicted Functional Partners:
ISM_02630
COG3492 Uncharacterized protein conserved in bacteria.
       0.769
ISM_02620
COG3931 Predicted N-formylglutamate amidohydrolase.
       0.694
ISM_03980
Hydratase/decarboxylase family protein; COG3971 2-keto-4-pentenoate hydratase.
  
 
 0.654
ISM_00050
Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
 
 0.594
ISM_13840
Fumarylacetoacetate hydrolase family protein; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
 
 0.529
ISM_08390
HpcH/HpaI aldolase family protein; COG3836 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family.
  
  
 0.488
ISM_02615
COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family.
       0.466
ISM_03595
MviM protein; COG0673 Predicted dehydrogenases and related proteins.
     
  0.427
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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