Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02710COG5598 Trimethylamine:corrinoid methyltransferase. (507 aa)    
Predicted Functional Partners:
ISM_08155
Flavin-containing monooxygenase; COG2072 Predicted flavoprotein involved in K+ transport.
     
  0.850
ISM_13450
Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein.
 
 
  0.827
ISM_02705
FAD dependent oxidoreductase/aminomethyl transferase; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family.
 
     0.710
ISM_16340
COG3894 Uncharacterized metal-binding protein.
 
     0.646
ISM_15125
Hypothetical protein.
 
     0.586
ISM_04820
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
     
  0.576
ISM_12595
Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family.
     
  0.576
ISM_13445
Hypothetical protein.
 
     0.516
ISM_11170
acyl-CoA synthetase, putative; COG1042 Acyl-CoA synthetase (NDP forming).
  
     0.469
ISM_02905
Molybdopterin oxidoreductase:Molydopterin dinucleotide-bindingregion; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
  0.422
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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