| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_02725 | ISM_02730 | ISM_02725 | ISM_02730 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.776 |
| ISM_02725 | ISM_02735 | ISM_02725 | ISM_02735 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.593 |
| ISM_02725 | ISM_13465 | ISM_02725 | ISM_13465 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.628 |
| ISM_02725 | ISM_15115 | ISM_02725 | ISM_15115 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.509 |
| ISM_02725 | ISM_15120 | ISM_02725 | ISM_15120 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | metF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.528 |
| ISM_02725 | tdh | ISM_02725 | ISM_02720 | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.768 |
| ISM_02730 | ISM_02725 | ISM_02730 | ISM_02725 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.776 |
| ISM_02730 | ISM_02735 | ISM_02730 | ISM_02735 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.541 |
| ISM_02730 | ISM_13445 | ISM_02730 | ISM_13445 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.777 |
| ISM_02730 | ISM_13450 | ISM_02730 | ISM_13450 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein. | 0.823 |
| ISM_02730 | ISM_13465 | ISM_02730 | ISM_13465 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Homocysteine S-methyltransferase family protein; COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain. | 0.654 |
| ISM_02730 | ISM_15115 | ISM_02730 | ISM_15115 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein; COG1410 Methionine synthase I, cobalamin-binding domain. | 0.759 |
| ISM_02730 | ISM_15120 | ISM_02730 | ISM_15120 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | metF-like protein; COG0685 5,10-methylenetetrahydrofolate reductase. | 0.546 |
| ISM_02730 | ISM_15125 | ISM_02730 | ISM_15125 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | Hypothetical protein. | 0.775 |
| ISM_02730 | ISM_16340 | ISM_02730 | ISM_16340 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | COG3894 Uncharacterized metal-binding protein. | 0.778 |
| ISM_02730 | tdh | ISM_02730 | ISM_02720 | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.443 |
| ISM_02735 | ISM_02725 | ISM_02735 | ISM_02725 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Aminomethyl transferase family protein; COG0665 Glycine/D-amino acid oxidases (deaminating); Belongs to the GcvT family. | 0.593 |
| ISM_02735 | ISM_02730 | ISM_02735 | ISM_02730 | COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.541 |
| ISM_13445 | ISM_02730 | ISM_13445 | ISM_02730 | Hypothetical protein. | Hypothetical protein; COG5598 Trimethylamine:corrinoid methyltransferase; Belongs to the trimethylamine methyltransferase family. | 0.777 |
| ISM_13445 | ISM_13450 | ISM_13445 | ISM_13450 | Hypothetical protein. | Corrinoid methyltransferase protein, putative; COG5012 Predicted cobalamin binding protein. | 0.924 |