Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_02745Histidine utilization repressor; COG2188 Transcriptional regulators. (229 aa)    
Predicted Functional Partners:
hutI
COG1228 Imidazolonepropionase and related amidohydrolases.
 
 
 0.881
hutH
COG2986 Histidine ammonia-lyase.
 
  
 0.817
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.787
ISM_02740
Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
 
  
 0.786
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
  0.626
ISM_07160
COG3741 N-formylglutamate amidohydrolase.
  
 
 0.532
ISM_04415
DNA-binding protein, putative; COG1396 Predicted transcriptional regulators.
  
  
 0.522
ISM_12675
COG1396 Predicted transcriptional regulators.
  
  
 0.522
ISM_02775
D-isomer specific 2-hydroxyacid dehydrogenase family protein; COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases.
    
  0.482
ISM_02750
Rod shape-determining protein MreB; COG1077 Actin-like ATPase involved in cell morphogenesis.
       0.417
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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