Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_02845Protease, putative; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone. (172 aa)    
Predicted Functional Partners:
ISM_06840
Hypothetical protein; COG0802 Predicted ATPase or kinase.
 
 
 0.985
tsaD
O-sialoglycoprotein endopeptidase, putative; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
 
 
 0.952
ISM_02840
Ribosomal-protein-alanine acetyltransferase, putative.
  
  
 0.881
ISM_02850
nifU domain protein; COG0694 Thioredoxin-like proteins and domains.
     
 0.741
ISM_02835
COG1280 Putative threonine efflux protein.
       0.618
ISM_02825
Hypothetical protein.
 
     0.615
tadA
Cytidine and deoxycytidylate deaminase family protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
  
 0.577
ISM_02855
COG0589 Universal stress protein UspA and related nucleotide-binding proteins.
       0.559
ISM_17220
COG0340 Biotin-(acetyl-CoA carboxylase) ligase.
  
    0.559
ISM_09736
COG1573 Uracil-DNA glycosylase.
  
    0.504
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.