Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_02855COG0589 Universal stress protein UspA and related nucleotide-binding proteins. (151 aa)    
Predicted Functional Partners:
ISM_02825
Hypothetical protein.
 
     0.857
ISM_02830
Membrane protein; COG0730 Predicted permeases.
 
     0.835
ISM_03950
Membrane protein; COG0730 Predicted permeases.
 
     0.784
ISM_02850
nifU domain protein; COG0694 Thioredoxin-like proteins and domains.
     
 0.646
ISM_02465
Hypothetical protein.
  
     0.559
ISM_02845
Protease, putative; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.
       0.559
ISM_02840
Ribosomal-protein-alanine acetyltransferase, putative.
       0.554
ISM_02865
Probable molybdopterin biosynthesis protein; COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2.
  
    0.549
ISM_02860
Peptidyl-dipeptidase, putative; COG0339 Zn-dependent oligopeptidases.
       0.539
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
       0.539
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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