Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene co-occurrence
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Score
ISM_03045Putative manganese transport system permease protein. (302 aa)    
Predicted Functional Partners:
ISM_03050
COG1257 Hydroxymethylglutaryl-CoA reductase.
 
   
 0.957
ISM_03035
Hypothetical protein; COG5379 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase.
 
     0.952
ISM_03040
COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
 
     0.949
ISM_03025
Hypothetical protein; COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit.
 
    0.928
ISM_03030
Hypothetical protein; COG0170 Dolichol kinase.
 
   
 0.924
ISM_03020
AMP-ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
   
 0.906
ISM_13185
Electrotransfer ubiquinone oxidoreductase family protein; Accepts electrons from ETF and reduces ubiquinone.
  
 
 0.632
ISM_16740
Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins.
    
 0.617
ISM_13030
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.549
lgt
Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family.
  
    0.547
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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