STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03050COG1257 Hydroxymethylglutaryl-CoA reductase. (421 aa)    
Predicted Functional Partners:
ISM_03045
Putative manganese transport system permease protein.
 
   
 0.958
ISM_03035
Hypothetical protein; COG5379 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase.
 
     0.950
ISM_03040
COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase.
 
     0.944
ISM_03025
Hypothetical protein; COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit.
 
     0.916
ISM_03030
Hypothetical protein; COG0170 Dolichol kinase.
 
     0.907
ISM_03020
AMP-ligase; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
     0.876
ISM_09526
Decaprenyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
 
 
 0.659
ISM_15535
Farnesyl diphosphate synthase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.
  
 
 0.611
ISM_11250
Hypothetical protein; COG0464 ATPases of the AAA+ class.
    
 
 0.597
ISM_17790
COG0464 ATPases of the AAA+ class.
    
 
 0.597
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.