Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_03065Membrane protein, putative. (249 aa)    
Predicted Functional Partners:
ISM_03060
Mercuric reductase, putative; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
   
 0.994
ISM_03055
COG0642 Signal transduction histidine kinase.
       0.746
ISM_12135
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
   
 0.745
ISM_05085
COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
   
 0.644
ISM_10850
COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes.
    
 0.624
rpmH
COG0230 Ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
       0.573
ISM_05560
Glycosyl transferase, group 2 family protein; COG0463 Glycosyltransferases involved in cell wall biogenesis.
 
   
 0.552
ISM_03075
Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.
       0.486
ISM_09411
Hypothetical protein.
 
 
 
 0.486
ISM_03495
COG1183 Phosphatidylserine synthase.
    
  0.479
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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