STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03150ErfK/YbiS/YcfS/YnhG family protein; COG1376 Uncharacterized protein conserved in bacteria. (176 aa)    
Predicted Functional Partners:
ISM_06595
ErfK/YbiS/YcfS/YnhG family protein; COG3034 Uncharacterized protein conserved in bacteria.
 
  
 0.706
ISM_13715
ErfK/YbiS/YcfS/YnhG family protein; COG3034 Uncharacterized protein conserved in bacteria.
 
  
 0.693
ISM_17605
ErfK/YbiS/YcfS/YnhG family protein; COG3034 Uncharacterized protein conserved in bacteria.
 
  
 0.693
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
       0.472
mepA
COG3770 Murein endopeptidase.
  
     0.461
ISM_06590
Lipoprotein, putative; COG2340 Uncharacterized protein with SCP/PR1 domains.
 
     0.455
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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