STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03160COG1788 Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit. (231 aa)    
Predicted Functional Partners:
ISM_03165
COG2057 Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit.
 0.999
ISM_02060
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
  
 
 0.955
ISM_14265
hydroxymethylglutaryl-CoA lyase; COG0119 Isopropylmalate/homocitrate/citramalate synthases.
  
 
 0.946
ISM_01470
COG1250 3-hydroxyacyl-CoA dehydrogenase.
  
 
 0.918
ISM_04115
D-beta-hydroxybutyrate dehydrogenase, putative; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 0.909
ISM_09496
acetoacetyl-CoA reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
    
 0.909
ISM_04125
3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 
 0.895
ISM_15675
COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
 
  
 0.875
ISM_11415
Hypothetical protein; COG1454 Alcohol dehydrogenase, class IV.
  
 
 0.833
ISM_06905
Beta-ketothiolase; COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.806
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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