close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03220TPR domain protein; COG0457 FOG: TPR repeat. (182 aa)    
Predicted Functional Partners:
ISM_03210
Type II/IV secretion system protein, TadC subfamily protein; COG4965 Flp pilus assembly protein TadB.
 
  
 0.933
ISM_03225
Lipoprotein, putative; COG0457 FOG: TPR repeat.
 
     0.931
ISM_03200
ATPase, putative; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
 
  
 0.922
ISM_03230
Membrane protein, putative.
 
   
 0.910
ISM_03215
Type II/IV secretion system protein, TadC subfamily protein; COG2064 Flp pilus assembly protein TadC.
 
  
 0.907
ISM_03235
Hypothetical protein; COG0606 Predicted ATPase with chaperone activity.
 
     0.841
ISM_03190
Bacterial type II/III secretion system protein; COG4964 Flp pilus assembly protein, secretin CpaC; Belongs to the bacterial secretin family.
 
  
 0.840
ISM_03185
CpaB family protein; COG3745 Flp pilus assembly protein CpaB.
 
  
 0.839
ISM_03205
Type II/IV secretion system protein, TadA subfamily protein; COG4962 Flp pilus assembly protein, ATPase CpaF.
 
  
 0.766
ISM_03195
OmpA family protein; COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins.
 
     0.765
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.