STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03250Hypothetical protein; COG3279 Response regulator of the LytR/AlgR family. (233 aa)    
Predicted Functional Partners:
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
    
 0.816
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
   0.771
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
  
 0.670
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
    
 0.642
sfsA
COG1489 DNA-binding protein, stimulates sugar fermentation; Belongs to the SfsA family.
    
   0.533
ISM_03255
Phenylacetic acid degradation-related protein; COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism.
       0.493
ISM_02180
Hypothetical protein.
  
     0.428
ISM_03765
Two component diguanylate cyclase; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain.
  
  
 0.409
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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