| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03275 | ISM_03290 | ISM_03275 | ISM_03290 | COG4106 Trans-aconitate methyltransferase. | COG1729 Uncharacterized protein conserved in bacteria. | 0.524 |
| ISM_03275 | ftsH | ISM_03275 | ISM_03280 | COG4106 Trans-aconitate methyltransferase. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.831 |
| ISM_03275 | pal | ISM_03275 | ISM_03295 | COG4106 Trans-aconitate methyltransferase. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.456 |
| ISM_03275 | tilS | ISM_03275 | ISM_03285 | COG4106 Trans-aconitate methyltransferase. | PP-loop family protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.629 |
| ISM_03290 | ISM_03275 | ISM_03290 | ISM_03275 | COG1729 Uncharacterized protein conserved in bacteria. | COG4106 Trans-aconitate methyltransferase. | 0.524 |
| ISM_03290 | ISM_03305 | ISM_03290 | ISM_03305 | COG1729 Uncharacterized protein conserved in bacteria. | tonB domain protein, putative. | 0.824 |
| ISM_03290 | ftsH | ISM_03290 | ISM_03280 | COG1729 Uncharacterized protein conserved in bacteria. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.633 |
| ISM_03290 | pal | ISM_03290 | ISM_03295 | COG1729 Uncharacterized protein conserved in bacteria. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.799 |
| ISM_03290 | tilS | ISM_03290 | ISM_03285 | COG1729 Uncharacterized protein conserved in bacteria. | PP-loop family protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.778 |
| ISM_03290 | tolB | ISM_03290 | ISM_03300 | COG1729 Uncharacterized protein conserved in bacteria. | Translocation protein TolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.946 |
| ISM_03305 | ISM_03290 | ISM_03305 | ISM_03290 | tonB domain protein, putative. | COG1729 Uncharacterized protein conserved in bacteria. | 0.824 |
| ISM_03305 | ftsH | ISM_03305 | ISM_03280 | tonB domain protein, putative. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.460 |
| ISM_03305 | pal | ISM_03305 | ISM_03295 | tonB domain protein, putative. | Peptidoglycan-associated lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.863 |
| ISM_03305 | tilS | ISM_03305 | ISM_03285 | tonB domain protein, putative. | PP-loop family protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.655 |
| ISM_03305 | tolB | ISM_03305 | ISM_03300 | tonB domain protein, putative. | Translocation protein TolB precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.975 |
| ISM_06100 | ftsH | ISM_06100 | ISM_03280 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | 0.405 |
| ISM_06100 | guaA | ISM_06100 | ISM_16255 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.912 |
| ISM_06100 | tilS | ISM_06100 | ISM_03285 | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | PP-loop family protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.724 |
| ISM_10631 | tilS | ISM_10631 | ISM_03285 | COG2104 Sulfur transfer protein involved in thiamine biosynthesis. | PP-loop family protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. | 0.893 |
| ftsH | ISM_03275 | ISM_03280 | ISM_03275 | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. | COG4106 Trans-aconitate methyltransferase. | 0.831 |