| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03325 | ISM_03330 | ISM_03325 | ISM_03330 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | 0.999 |
| ISM_03325 | ISM_03340 | ISM_03325 | ISM_03340 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | COG1802 Transcriptional regulators. | 0.500 |
| ISM_03325 | pxpA | ISM_03325 | ISM_03335 | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.998 |
| ISM_03330 | ISM_03325 | ISM_03330 | ISM_03325 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | 0.999 |
| ISM_03330 | ISM_03340 | ISM_03330 | ISM_03340 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | COG1802 Transcriptional regulators. | 0.500 |
| ISM_03330 | pxpA | ISM_03330 | ISM_03335 | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.998 |
| ISM_03340 | ISM_03325 | ISM_03340 | ISM_03325 | COG1802 Transcriptional regulators. | Urea amidolyase; COG1984 Allophanate hydrolase subunit 2. | 0.500 |
| ISM_03340 | ISM_03330 | ISM_03340 | ISM_03330 | COG1802 Transcriptional regulators. | Hypothetical protein; COG2049 Allophanate hydrolase subunit 1. | 0.500 |
| ISM_03340 | ISM_03345 | ISM_03340 | ISM_03345 | COG1802 Transcriptional regulators. | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | 0.510 |
| ISM_03340 | ISM_03985 | ISM_03340 | ISM_03985 | COG1802 Transcriptional regulators. | Transcriptional regulatory protein; COG1802 Transcriptional regulators. | 0.771 |
| ISM_03340 | ISM_06335 | ISM_03340 | ISM_06335 | COG1802 Transcriptional regulators. | Transcriptional regulator, GntR family protein; COG1802 Transcriptional regulators. | 0.755 |
| ISM_03340 | ISM_10296 | ISM_03340 | ISM_10296 | COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.760 |
| ISM_03340 | ISM_13645 | ISM_03340 | ISM_13645 | COG1802 Transcriptional regulators. | Pyruvate dehydrogenase complex repressor; COG2186 Transcriptional regulators. | 0.591 |
| ISM_03340 | ISM_15325 | ISM_03340 | ISM_15325 | COG1802 Transcriptional regulators. | Regulator for uxu operon; COG2186 Transcriptional regulators. | 0.563 |
| ISM_03340 | prmC | ISM_03340 | ISM_14685 | COG1802 Transcriptional regulators. | Modification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.551 |
| ISM_03340 | pxpA | ISM_03340 | ISM_03335 | COG1802 Transcriptional regulators. | Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.500 |
| ISM_03345 | ISM_03340 | ISM_03345 | ISM_03340 | Hypothetical protein; COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]. | COG1802 Transcriptional regulators. | 0.510 |
| ISM_03985 | ISM_03340 | ISM_03985 | ISM_03340 | Transcriptional regulatory protein; COG1802 Transcriptional regulators. | COG1802 Transcriptional regulators. | 0.771 |
| ISM_03985 | ISM_15325 | ISM_03985 | ISM_15325 | Transcriptional regulatory protein; COG1802 Transcriptional regulators. | Regulator for uxu operon; COG2186 Transcriptional regulators. | 0.615 |
| ISM_03985 | prmC | ISM_03985 | ISM_14685 | Transcriptional regulatory protein; COG1802 Transcriptional regulators. | Modification methylase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.603 |