| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00290 | ISM_03380 | ISM_00290 | ISM_03380 | COG2071 Predicted glutamine amidotransferases. | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.535 |
| ISM_00290 | ISM_10271 | ISM_00290 | ISM_10271 | COG2071 Predicted glutamine amidotransferases. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.480 |
| ISM_03375 | ISM_03380 | ISM_03375 | ISM_03380 | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.531 |
| ISM_03375 | ISM_03385 | ISM_03375 | ISM_03385 | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.431 |
| ISM_03380 | ISM_00290 | ISM_03380 | ISM_00290 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COG2071 Predicted glutamine amidotransferases. | 0.535 |
| ISM_03380 | ISM_03375 | ISM_03380 | ISM_03375 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.531 |
| ISM_03380 | ISM_03385 | ISM_03380 | ISM_03385 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.580 |
| ISM_03380 | ISM_03680 | ISM_03380 | ISM_03680 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.609 |
| ISM_03380 | ISM_10271 | ISM_03380 | ISM_10271 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.559 |
| ISM_03380 | ISM_10775 | ISM_03380 | ISM_10775 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family. | 0.609 |
| ISM_03380 | ISM_15170 | ISM_03380 | ISM_15170 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 5-aminolevulinate synthase; COG0156 7-keto-8-aminopelargonate synthetase and related enzymes. | 0.616 |
| ISM_03380 | asd | ISM_03380 | ISM_02370 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.576 |
| ISM_03380 | gcvP | ISM_03380 | ISM_05725 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.530 |
| ISM_03380 | kbl | ISM_03380 | ISM_07815 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.616 |
| ISM_03385 | ISM_03375 | ISM_03385 | ISM_03375 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Acetylpolyamine aminohydrolase; COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein. | 0.431 |
| ISM_03385 | ISM_03380 | ISM_03385 | ISM_03380 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.580 |
| ISM_03680 | ISM_03380 | ISM_03680 | ISM_03380 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.609 |
| ISM_03680 | ISM_10271 | ISM_03680 | ISM_10271 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Putative aminotransferase protein; COG0160 4-aminobutyrate aminotransferase and related aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.581 |
| ISM_03680 | asd | ISM_03680 | ISM_02370 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.442 |
| ISM_03680 | gcvP | ISM_03680 | ISM_05725 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.537 |