| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_01185 | ISM_02060 | ISM_01185 | ISM_02060 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.661 |
| ISM_01185 | ISM_03385 | ISM_01185 | ISM_03385 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.605 |
| ISM_01185 | ISM_04125 | ISM_01185 | ISM_04125 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.661 |
| ISM_01185 | ISM_06100 | ISM_01185 | ISM_06100 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.451 |
| ISM_01185 | ISM_08180 | ISM_01185 | ISM_08180 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.772 |
| ISM_01185 | ISM_16740 | ISM_01185 | ISM_16740 | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.968 |
| ISM_02060 | ISM_01185 | ISM_02060 | ISM_01185 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.661 |
| ISM_02060 | ISM_03385 | ISM_02060 | ISM_03385 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.608 |
| ISM_02060 | ISM_04125 | ISM_02060 | ISM_04125 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 3-hydroxyacyl-CoA dehydrogenase; COG1024 Enoyl-CoA hydratase/carnithine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.884 |
| ISM_02060 | ISM_06100 | ISM_02060 | ISM_06100 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.451 |
| ISM_02060 | ISM_08180 | ISM_02060 | ISM_08180 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.772 |
| ISM_02060 | ISM_16740 | ISM_02060 | ISM_16740 | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.968 |
| ISM_02660 | ISM_03385 | ISM_02660 | ISM_03385 | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.541 |
| ISM_02660 | ISM_08180 | ISM_02660 | ISM_08180 | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.569 |
| ISM_02660 | ISM_16740 | ISM_02660 | ISM_16740 | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.641 |
| ISM_02660 | acpP | ISM_02660 | ISM_01130 | Ubiquinol--cytochrome c reductase, cytochrome B; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.751 |
| ISM_03380 | ISM_03385 | ISM_03380 | ISM_03385 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.580 |
| ISM_03380 | ISM_06100 | ISM_03380 | ISM_06100 | Hypothetical protein; COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.653 |
| ISM_03385 | ISM_01185 | ISM_03385 | ISM_01185 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Hypothetical protein; COG1250 3-hydroxyacyl-CoA dehydrogenase. | 0.605 |
| ISM_03385 | ISM_02060 | ISM_03385 | ISM_02060 | Oxidoreductase, short chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase. | 0.608 |