| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03400 | ISM_03405 | ISM_03400 | ISM_03405 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.883 |
| ISM_03400 | ISM_03410 | ISM_03400 | ISM_03410 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | 0.943 |
| ISM_03400 | ISM_03415 | ISM_03400 | ISM_03415 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family. | 0.816 |
| ISM_03400 | ISM_03860 | ISM_03400 | ISM_03860 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.817 |
| ISM_03400 | ISM_07075 | ISM_03400 | ISM_07075 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | COG1004 Predicted UDP-glucose 6-dehydrogenase. | 0.941 |
| ISM_03400 | ISM_16740 | ISM_03400 | ISM_16740 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.894 |
| ISM_03400 | gmd | ISM_03400 | ISM_14120 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.809 |
| ISM_03400 | rpsC | ISM_03400 | ISM_01805 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.802 |
| ISM_03400 | rpsQ | ISM_03400 | ISM_01760 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | Ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. | 0.796 |
| ISM_03400 | rpsS | ISM_03400 | ISM_01815 | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.829 |
| ISM_03405 | ISM_03400 | ISM_03405 | ISM_03400 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.883 |
| ISM_03405 | ISM_03410 | ISM_03405 | ISM_03410 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | 0.831 |
| ISM_03405 | ISM_03415 | ISM_03405 | ISM_03415 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family. | 0.744 |
| ISM_03405 | ISM_03860 | ISM_03405 | ISM_03860 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. | 0.494 |
| ISM_03405 | ISM_07075 | ISM_03405 | ISM_07075 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | COG1004 Predicted UDP-glucose 6-dehydrogenase. | 0.718 |
| ISM_03405 | gmd | ISM_03405 | ISM_14120 | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | NAD-dependent epimerase/dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. | 0.414 |
| ISM_03410 | ISM_03400 | ISM_03410 | ISM_03400 | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases. | 0.943 |
| ISM_03410 | ISM_03405 | ISM_03410 | ISM_03405 | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.831 |
| ISM_03410 | ISM_03415 | ISM_03410 | ISM_03415 | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family. | 0.984 |
| ISM_03410 | ISM_07075 | ISM_03410 | ISM_07075 | Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis. | COG1004 Predicted UDP-glucose 6-dehydrogenase. | 0.546 |