Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_03405COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (332 aa)    
Predicted Functional Partners:
ISM_03400
NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases.
 
0.883
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
 
 0.861
ISM_03410
Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
 
   
 0.831
ISM_07025
COG1210 UDP-glucose pyrophosphorylase.
 
  
 0.809
ISM_03415
COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.744
ISM_07075
COG1004 Predicted UDP-glucose 6-dehydrogenase.
 
 
 0.718
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
   
 0.708
ISM_03855
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
    
 0.683
ISM_03865
COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
  
 
 0.656
ISM_07800
S1 RNA binding domain protein; COG2183 Transcriptional accessory protein.
   
   0.535
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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