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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03405COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (332 aa)    
Predicted Functional Partners:
ISM_03400
NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases.
 
0.900
ISM_07025
COG1210 UDP-glucose pyrophosphorylase.
 
  
 0.863
ISM_03410
Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
 
   
 0.832
ISM_03415
COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family.
 
     0.741
ISM_07075
COG1004 Predicted UDP-glucose 6-dehydrogenase.
 
 
 0.722
ISM_03865
COG1088 dTDP-D-glucose 4,6-dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
 
0.632
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
    
 
 0.614
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
  
 0.607
fcl
NAD-dependent epimerase/dehydratase family protein; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.
 
 0.598
ISM_03955
Hypothetical protein; COG0451 Nucleoside-diphosphate-sugar epimerases.
 
0.568
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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