Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ISM_03415COG4124 Beta-mannanase; Belongs to the glycosyl hydrolase 26 family. (290 aa)    
Predicted Functional Partners:
ISM_03410
Cellulose synthase-like protein; COG1215 Glycosyltransferases, probably involved in cell wall biogenesis.
  
  0.984
ISM_03400
NAD-dependent epimerase/dehydratase family protein; COG0451 Nucleoside-diphosphate-sugar epimerases.
 
     0.816
ISM_03405
COG1087 UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
     0.744
ISM_03395
Hypothetical protein; COG0587 DNA polymerase III, alpha subunit.
  
     0.690
ISM_17070
Hypothetical protein.
  
     0.627
ISM_17085
Hypothetical protein.
  
     0.608
ISM_07075
COG1004 Predicted UDP-glucose 6-dehydrogenase.
 
  
  0.524
ISM_03535
Hypothetical protein.
  
 
 0.518
ISM_16420
beta-N-acetylhexosaminidase, putative; COG1472 Beta-glucosidase-related glycosidases.
     
 0.474
ISM_05705
Lipolytic enzyme, G-D-S-L family protein; COG2755 Lysophospholipase L1 and related esterases.
    
 0.453
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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