| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_00215 | ISM_03430 | ISM_00215 | ISM_03430 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.560 |
| ISM_00215 | ISM_05910 | ISM_00215 | ISM_05910 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.997 |
| ISM_00215 | ISM_06625 | ISM_00215 | ISM_06625 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Response regulator; COG0784 FOG: CheY-like receiver. | 0.993 |
| ISM_00215 | ISM_06925 | ISM_00215 | ISM_06925 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.999 |
| ISM_00215 | cysC | ISM_00215 | ISM_11065 | Hypothetical protein; COG2199 FOG: GGDEF domain. | Bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; Catalyzes the synthesis of activated sulfate. | 0.439 |
| ISM_00440 | ISM_03430 | ISM_00440 | ISM_03430 | ABC transporter, permease protein, HisMQ family protein; COG4215 ABC-type arginine transport system, permease component. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.479 |
| ISM_02460 | ISM_03430 | ISM_02460 | ISM_03430 | COG1360 Flagellar motor protein. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.556 |
| ISM_02460 | ISM_05910 | ISM_02460 | ISM_05910 | COG1360 Flagellar motor protein. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.603 |
| ISM_02460 | ISM_06925 | ISM_02460 | ISM_06925 | COG1360 Flagellar motor protein. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.715 |
| ISM_03425 | ISM_03430 | ISM_03425 | ISM_03430 | Hypothetical protein. | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | 0.542 |
| ISM_03425 | ISM_03435 | ISM_03425 | ISM_03435 | Hypothetical protein. | Hypothetical protein; COG0053 Predicted Co/Zn/Cd cation transporters. | 0.542 |
| ISM_03430 | ISM_00215 | ISM_03430 | ISM_00215 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Hypothetical protein; COG2199 FOG: GGDEF domain. | 0.560 |
| ISM_03430 | ISM_00440 | ISM_03430 | ISM_00440 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | ABC transporter, permease protein, HisMQ family protein; COG4215 ABC-type arginine transport system, permease component. | 0.479 |
| ISM_03430 | ISM_02460 | ISM_03430 | ISM_02460 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | COG1360 Flagellar motor protein. | 0.556 |
| ISM_03430 | ISM_03425 | ISM_03430 | ISM_03425 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Hypothetical protein. | 0.542 |
| ISM_03430 | ISM_03435 | ISM_03430 | ISM_03435 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Hypothetical protein; COG0053 Predicted Co/Zn/Cd cation transporters. | 0.957 |
| ISM_03430 | ISM_05910 | ISM_03430 | ISM_05910 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.557 |
| ISM_03430 | ISM_06165 | ISM_03430 | ISM_06165 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Oxidoreductase, short-chain dehydrogenase/reductase family protein; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.511 |
| ISM_03430 | ISM_06625 | ISM_03430 | ISM_06625 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Response regulator; COG0784 FOG: CheY-like receiver. | 0.466 |
| ISM_03430 | ISM_06925 | ISM_03430 | ISM_06925 | Hypothetical protein; COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain. | Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase. | 0.668 |