| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_01450 | ISM_01455 | COG2086 Electron transfer flavoprotein, beta subunit. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.999 |
| ISM_01450 | ISM_03515 | COG2086 Electron transfer flavoprotein, beta subunit. | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.696 |
| ISM_01450 | ISM_04820 | COG2086 Electron transfer flavoprotein, beta subunit. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.750 |
| ISM_01450 | ISM_07825 | COG2086 Electron transfer flavoprotein, beta subunit. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.801 |
| ISM_01450 | ISM_12240 | COG2086 Electron transfer flavoprotein, beta subunit. | Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.984 |
| ISM_01450 | ISM_12680 | COG2086 Electron transfer flavoprotein, beta subunit. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.984 |
| ISM_01455 | ISM_01450 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.999 |
| ISM_01455 | ISM_03515 | COG2025 Electron transfer flavoprotein, alpha subunit. | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.623 |
| ISM_01455 | ISM_04820 | COG2025 Electron transfer flavoprotein, alpha subunit. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.789 |
| ISM_01455 | ISM_07825 | COG2025 Electron transfer flavoprotein, alpha subunit. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.801 |
| ISM_01455 | ISM_12240 | COG2025 Electron transfer flavoprotein, alpha subunit. | Hypothetical protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.964 |
| ISM_01455 | ISM_12680 | COG2025 Electron transfer flavoprotein, alpha subunit. | COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.964 |
| ISM_03515 | ISM_01450 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG2086 Electron transfer flavoprotein, beta subunit. | 0.696 |
| ISM_03515 | ISM_01455 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG2025 Electron transfer flavoprotein, alpha subunit. | 0.623 |
| ISM_03515 | ISM_03520 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Putative DegT/DnrJ/EryC1/StrS family aminotransferase protein; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family. | 0.542 |
| ISM_03515 | ISM_03525 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | COG0110 Acetyltransferase (isoleucine patch superfamily). | 0.542 |
| ISM_03515 | ISM_03530 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Putative UDP-galactose phosphate transferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis. | 0.542 |
| ISM_03515 | ISM_04820 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Probable methylamine; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.461 |
| ISM_03515 | ISM_06100 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.652 |
| ISM_03515 | ISM_07825 | Oxidoreductase, FAD/FMN-binding protein; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | Oxidoreductase, FMN-binding/pyridine nucleotide-disulfideoxidoreductase; COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family. | 0.413 |