STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03550Hypothetical protein; COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains. (604 aa)    
Predicted Functional Partners:
ISM_10631
COG2104 Sulfur transfer protein involved in thiamine biosynthesis.
  
   0.893
ISM_03545
COG0438 Glycosyltransferase.
 
    0.849
ISM_03555
COG0438 Glycosyltransferase.
  
    0.753
glmM
Phosphoglucomutase/phosphomannomutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
   
  0.751
pgi
COG0166 Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
  0.725
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
    
  0.724
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
 
 0.688
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  
  0.613
ISM_13030
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.560
pth
peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
  
 0.525
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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