Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ISM_03635Hypothetical protein. (311 aa)    
Predicted Functional Partners:
ISM_03620
COG1250 3-hydroxyacyl-CoA dehydrogenase.
 
  
 0.831
ISM_03640
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
    0.748
ISM_03645
Sulfatase; COG3119 Arylsulfatase A and related enzymes.
       0.746
ISM_03650
COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit.
       0.746
ISM_03625
Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
    0.680
ISM_03630
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
       0.678
ISM_02915
Hypothetical protein.
  
     0.626
lcdH
3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine.
 
 
 0.590
ISM_00330
Thioesterase superfamily protein; COG0824 Predicted thioesterase.
 
 
 0.565
ISM_14140
Hypothetical protein; COG1396 Predicted transcriptional regulators.
  
    0.545
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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