| node1 | node2 | node1 annotation | node2 annotation | score |
| ISM_03680 | ISM_03700 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | 0.649 |
| ISM_03680 | ISM_03925 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Probable oxidoreductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. | 0.647 |
| ISM_03680 | ISM_04975 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.643 |
| ISM_03680 | ISM_04990 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.715 |
| ISM_03680 | ISM_05875 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | phenylacetate-CoA ligase, putative; COG1541 Coenzyme F390 synthetase. | 0.758 |
| ISM_03680 | ISM_06100 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.675 |
| ISM_03680 | ISM_08325 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.656 |
| ISM_03680 | ISM_08755 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.707 |
| ISM_03680 | ISM_14750 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.666 |
| ISM_03680 | ISM_16740 | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | Non-ribosomal peptide synthase; COG3321 Polyketide synthase modules and related proteins. | 0.646 |
| ISM_03700 | ISM_03680 | COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.649 |
| ISM_03925 | ISM_03680 | Probable oxidoreductase; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.647 |
| ISM_04975 | ISM_03680 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.643 |
| ISM_04975 | ISM_04990 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
| ISM_04975 | ISM_08755 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG1448 Aspartate/tyrosine/aromatic aminotransferase. | 0.818 |
| ISM_04975 | ISM_14750 | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.933 |
| ISM_04990 | ISM_03680 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.715 |
| ISM_04990 | ISM_04975 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.999 |
| ISM_04990 | ISM_06100 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.452 |
| ISM_04990 | ISM_08325 | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | Bifunctional PutA protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.612 |