Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ISM_03685Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. (321 aa)    
Predicted Functional Partners:
ISM_03700
COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family.
 
     0.863
nadX
Hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
 
     0.841
ISM_03720
TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.792
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
     0.743
ISM_03715
TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.731
ISM_03695
Hypothetical protein.
       0.718
ISM_07480
COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.645
ISM_13115
Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.628
ISM_03670
Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.609
ISM_04210
Glycine cleavage system transcriptional activator; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.588
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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