STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03700COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; Belongs to the DapA family. (317 aa)    
Predicted Functional Partners:
dapB
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
 
 
 0.864
ISM_03685
Transcriptional regulator, LysR family protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
 
     0.863
nbaC
3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
 
     0.858
ISM_03715
TRAP dicarboxylate transporter, DctP subunit, putative; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.839
ISM_03720
TRAP dicarboxylate transporter, DctQ subunit; COG3090 TRAP-type C4-dicarboxylate transport system, small permease component.
 
     0.839
nadX
Hypothetical protein; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate.
 
     0.809
asd
Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.
  
 
 0.773
ISM_03705
Hypothetical protein; COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily.
       0.762
ISM_12920
COG0460 Homoserine dehydrogenase.
  
 
 0.666
ISM_03680
Hypothetical protein; COG1012 NAD-dependent aldehyde dehydrogenases.
 
 
 0.649
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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