Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03740Two component diguanylate cyclase; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain. (299 aa)    
Predicted Functional Partners:
ISM_04775
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
 0.955
ISM_12905
Multi-sensor Signal Transduction Histidine Kinase; COG2202 FOG: PAS/PAC domain.
 
 0.920
ISM_12885
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
 0.905
ISM_10556
Hypothetical protein; COG0642 Signal transduction histidine kinase.
 
 0.894
ISM_15585
Phosphate regulon sensor histidine kinase, putative; COG0642 Signal transduction histidine kinase.
 
 0.886
ISM_04780
PAS; COG0642 Signal transduction histidine kinase.
 
 0.876
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
 
 0.873
ISM_13545
COG0642 Signal transduction histidine kinase.
 
 0.840
ISM_05545
Histidine kinase/response regulator hybrid protein; COG2202 FOG: PAS/PAC domain.
  
 0.831
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
  
 0.830
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
Server load: low (8%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.