STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03755N-acylhomoserine lactone synthase; COG3916 N-acyl-L-homoserine lactone synthetase; Belongs to the autoinducer synthase family. (201 aa)    
Predicted Functional Partners:
ISM_15650
Autoinducer-binding transcriptional regulator, LuxR family protein; COG2771 DNA-binding HTH domain-containing proteins.
  
 
 0.917
ISM_15790
Transcriptional regulator, LuxR family/hydrolase, alpha/beta fold family; COG2771 DNA-binding HTH domain-containing proteins.
  
 
 0.867
ISM_06130
Modification methylase (Cytosine-specific methyltransferase; COG0270 Site-specific DNA methylase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.818
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
     
 0.783
ISM_05685
Hypothetical protein; COG5001 Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain.
    
 0.701
ISM_03760
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
 
  
 0.677
ISM_02740
Formiminoglutamate deiminase; COG0402 Cytosine deaminase and related metal-dependent hydrolases.
  
  
  0.655
ISM_06925
Sensor histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
     
 0.533
ISM_05910
Sensory box histidine kinase/response regulator; COG0642 Signal transduction histidine kinase.
     
 0.503
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
     
 0.470
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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