| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_03775 | ISM_03780 | ISM_03775 | ISM_03780 | Hypothetical protein. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.901 |
| ISM_03775 | ISM_05235 | ISM_03775 | ISM_05235 | Hypothetical protein. | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.547 |
| ISM_03775 | ISM_08490 | ISM_03775 | ISM_08490 | Hypothetical protein. | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.687 |
| ISM_03780 | ISM_03775 | ISM_03780 | ISM_03775 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Hypothetical protein. | 0.901 |
| ISM_03780 | ISM_05225 | ISM_03780 | ISM_05225 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.403 |
| ISM_03780 | ISM_05235 | ISM_03780 | ISM_05235 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.492 |
| ISM_03780 | ISM_08180 | ISM_03780 | ISM_08180 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | 0.456 |
| ISM_03780 | ISM_08490 | ISM_03780 | ISM_08490 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.498 |
| ISM_03780 | ftsZ | ISM_03780 | ISM_00580 | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.425 |
| ISM_05225 | ISM_03780 | ISM_05225 | ISM_03780 | Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.403 |
| ISM_05225 | ISM_05235 | ISM_05225 | ISM_05235 | Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.777 |
| ISM_05235 | ISM_03775 | ISM_05235 | ISM_03775 | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Hypothetical protein. | 0.547 |
| ISM_05235 | ISM_03780 | ISM_05235 | ISM_03780 | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.492 |
| ISM_05235 | ISM_05225 | ISM_05235 | ISM_05225 | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Hypothetical protein; COG0583 Transcriptional regulator; Belongs to the LysR transcriptional regulatory family. | 0.777 |
| ISM_05235 | ISM_08490 | ISM_05235 | ISM_08490 | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | 0.704 |
| ISM_08180 | ISM_03780 | ISM_08180 | ISM_03780 | Vanillate O-demethylase oxidoreductase; COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.456 |
| ISM_08490 | ISM_03775 | ISM_08490 | ISM_03775 | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | Hypothetical protein. | 0.687 |
| ISM_08490 | ISM_03780 | ISM_08490 | ISM_03780 | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.498 |
| ISM_08490 | ISM_05235 | ISM_08490 | ISM_05235 | Dioxygenase superfamily-like protein; COG0346 Lactoylglutathione lyase and related lyases. | Probable oxidoreductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.704 |
| ftsZ | ISM_03780 | ISM_00580 | ISM_03780 | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | Possible transcriptional regulator, TetR family protein; COG1309 Transcriptional regulator. | 0.425 |
