STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_03890COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases. (293 aa)    
Predicted Functional Partners:
ISM_03895
COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
  
 
  0.809
ISM_10915
COG1012 NAD-dependent aldehyde dehydrogenases.
  
 
  0.700
ISM_02060
enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase /3-hydroxybutyryl-CoA epimerase; COG1024 Enoyl-CoA hydratase/carnithine racemase.
  
 
 0.699
ISM_09180
COG1012 NAD-dependent aldehyde dehydrogenases.
   
 
  0.660
ISM_10875
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases; Belongs to the HIBADH-related family.
  
  
 
0.656
ISM_12940
COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
  
 
0.654
ISM_11170
acyl-CoA synthetase, putative; COG1042 Acyl-CoA synthetase (NDP forming).
    
  0.635
ISM_14750
COG0372 Citrate synthase; Belongs to the citrate synthase family.
  
 
  0.625
ISM_03885
Putative periplasmic substrate-binding transport protein; COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component.
 
     0.622
ISM_09070
Hypothetical protein; COG3622 Hydroxypyruvate isomerase; Belongs to the hyi family.
 
 
 0.599
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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