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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04040Hypothetical protein; COG1834 N-Dimethylarginine dimethylaminohydrolase. (312 aa)    
Predicted Functional Partners:
ISM_06100
Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1.
   
 
  0.834
ISM_13020
Hypothetical protein; COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase.
  
     0.669
ISM_04035
COG0747 ABC-type dipeptide transport system, periplasmic component.
       0.594
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.579
ISM_09346
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
     
 0.551
ISM_09661
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
     
 0.551
ISM_12990
Sarcosine oxidase, alpha subunit family protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; Belongs to the GcvT family.
     
 0.551
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.534
ISM_11605
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline.
    
 0.534
ISM_08375
phytanoyl-CoA dioxygenase family protein; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.
  
     0.507
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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