STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04070Hypothetical protein; COG3837 Uncharacterized conserved protein, contains double-stranded beta-helix domain. (150 aa)    
Predicted Functional Partners:
ISM_04075
Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases.
 
   
 0.940
ISM_04045
Probable substrate-binding protein; COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component.
 
     0.786
ISM_04055
ABC transporter permease protein; COG4177 ABC-type branched-chain amino acid transport system, permease component; Belongs to the binding-protein-dependent transport system permease family.
 
     0.780
ISM_04060
ABC transporter ATP-binding protein; COG0411 ABC-type branched-chain amino acid transport systems, ATPase component.
 
     0.779
ISM_04050
ABC transporter permease protein; COG0559 Branched-chain amino acid ABC-type transport system, permease components; Belongs to the binding-protein-dependent transport system permease family.
 
     0.761
ISM_04065
ABC transporter ATP-binding protein; COG0410 ABC-type branched-chain amino acid transport systems, ATPase component.
 
     0.758
rpoH
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
   0.532
ISM_02885
COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); Belongs to the sigma-70 factor family.
    
   0.532
rpoD
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.532
ISM_14135
Mannose-6-phosphate isomerase; COG0836 Mannose-1-phosphate guanylyltransferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
  0.476
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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