Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04160COG3667 Uncharacterized protein involved in copper resistance. (231 aa)    
Predicted Functional Partners:
ISM_04155
COG2132 Putative multicopper oxidases.
 
  
 0.974
ISM_04145
Copper-binding protein, plastocyanin/azurin family protein; COG4454 Uncharacterized copper-binding protein.
 
  
 0.905
ISM_17515
COG2132 Putative multicopper oxidases.
 
  
 0.797
ISM_11910
COG2132 Putative multicopper oxidases.
 
  
 0.790
ISM_17635
COG2132 Putative multicopper oxidases.
 
  
 0.753
ISM_17450
Hypothetical protein; COG2132 Putative multicopper oxidases.
  
  
 0.714
ISM_02960
Hypothetical protein; COG3450 Predicted enzyme of the cupin superfamily.
   
    0.509
ISM_03815
Hypothetical protein; COG3450 Predicted enzyme of the cupin superfamily.
   
    0.509
ISM_17435
COG2217 Cation transport ATPase.
 
   
 0.460
ISM_04150
Hypothetical protein.
       0.412
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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