Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ectCEctoine synthase; Catalyzes the circularization of gamma-N-acetyl-alpha,gamma- diaminobutyric acid (ADABA) to ectoine (1,4,5,6-tetrahydro-2-methyl-4- pyrimidine carboxylic acid), which is an excellent osmoprotectant. (135 aa)    
Predicted Functional Partners:
ectA
L-2,4-diaminobutyric acid acetyltransferase; Catalyzes the acetylation of L-2,4-diaminobutyrate (DABA) to gamma-N-acetyl-alpha,gamma-diaminobutyric acid (ADABA) with acetyl coenzyme A.
 
 
  0.984
ISM_04200
Putative L-proline 4-hydroxylase.
 
  
 0.965
ISM_04190
Diaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
   
 0.956
ISM_04205
COG0527 Aspartokinases.
 
   
 0.928
ISM_07880
Hypothetical protein; COG0006 Xaa-Pro aminopeptidase.
  
  
  0.889
ISM_04180
Transcriptional regulator, MarR family protein; COG1846 Transcriptional regulators.
 
     0.835
ISM_08375
phytanoyl-CoA dioxygenase family protein; COG5285 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin.
    
 0.663
ISM_03530
Putative UDP-galactose phosphate transferase; COG2148 Sugar transferases involved in lipopolysaccharide synthesis.
  
 
 0.539
ISM_05610
COG1086 Predicted nucleoside-diphosphate sugar epimerases.
  
 
 0.473
ISM_03855
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.457
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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