| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ISM_04220 | ISM_04225 | ISM_04220 | ISM_04225 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | 0.998 |
| ISM_04220 | ISM_04230 | ISM_04220 | ISM_04230 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Hemin degrading factor; COG3720 Putative heme degradation protein. | 0.940 |
| ISM_04220 | ISM_04235 | ISM_04220 | ISM_04235 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative Hemin receptor protein HmuR; COG1629 Outer membrane receptor proteins, mostly Fe transport. | 0.829 |
| ISM_04220 | ISM_04245 | ISM_04220 | ISM_04245 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | COG0810 Periplasmic protein TonB, links inner and outer membranes. | 0.542 |
| ISM_04220 | ISM_04250 | ISM_04220 | ISM_04250 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | COG0848 Biopolymer transport protein. | 0.453 |
| ISM_04220 | ISM_04255 | ISM_04220 | ISM_04255 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Hypothetical protein; COG0460 Homoserine dehydrogenase. | 0.495 |
| ISM_04220 | ISM_07735 | ISM_04220 | ISM_07735 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Iron ABC transporter, ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.998 |
| ISM_04220 | hmuV | ISM_04220 | ISM_04215 | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | Putative hemin transport system atp-binding abc transporter protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.998 |
| ISM_04225 | ISM_04220 | ISM_04225 | ISM_04220 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.998 |
| ISM_04225 | ISM_04230 | ISM_04225 | ISM_04230 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Hemin degrading factor; COG3720 Putative heme degradation protein. | 0.994 |
| ISM_04225 | ISM_04235 | ISM_04225 | ISM_04235 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Putative Hemin receptor protein HmuR; COG1629 Outer membrane receptor proteins, mostly Fe transport. | 0.914 |
| ISM_04225 | ISM_04245 | ISM_04225 | ISM_04245 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | COG0810 Periplasmic protein TonB, links inner and outer membranes. | 0.719 |
| ISM_04225 | ISM_04250 | ISM_04225 | ISM_04250 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | COG0848 Biopolymer transport protein. | 0.715 |
| ISM_04225 | ISM_04255 | ISM_04225 | ISM_04255 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Hypothetical protein; COG0460 Homoserine dehydrogenase. | 0.665 |
| ISM_04225 | ISM_04265 | ISM_04225 | ISM_04265 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | COG0718 Uncharacterized protein conserved in bacteria. | 0.654 |
| ISM_04225 | ISM_07735 | ISM_04225 | ISM_07735 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Iron ABC transporter, ATP-binding protein; COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components. | 0.965 |
| ISM_04225 | ISM_07740 | ISM_04225 | ISM_07740 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Iron ABC transporter, permease protein, putative; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.987 |
| ISM_04225 | hmuV | ISM_04225 | ISM_04215 | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | Putative hemin transport system atp-binding abc transporter protein; Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system. | 0.998 |
| ISM_04230 | ISM_04220 | ISM_04230 | ISM_04220 | Hemin degrading factor; COG3720 Putative heme degradation protein. | Permease protein of ABC transporter; COG0609 ABC-type Fe3+-siderophore transport system, permease component; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. | 0.940 |
| ISM_04230 | ISM_04225 | ISM_04230 | ISM_04225 | Hemin degrading factor; COG3720 Putative heme degradation protein. | Putative hemin binding periplasmic transmembrane protein; COG4558 ABC-type hemin transport system, periplasmic component. | 0.994 |