STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ISM_04255Hypothetical protein; COG0460 Homoserine dehydrogenase. (128 aa)    
Predicted Functional Partners:
ISM_04245
COG0810 Periplasmic protein TonB, links inner and outer membranes.
 
 
 0.998
ISM_04260
MotA/TolQ/ExbB proton channel family domain protein; COG0811 Biopolymer transport proteins.
 
 
 0.998
ISM_03315
Proton transporter TolQ; COG0811 Biopolymer transport proteins.
  
 
 0.965
ISM_04250
COG0848 Biopolymer transport protein.
 
     0.965
ISM_03305
tonB domain protein, putative.
  
 
 0.963
ISM_04265
COG0718 Uncharacterized protein conserved in bacteria.
 
     0.963
ISM_04235
Putative Hemin receptor protein HmuR; COG1629 Outer membrane receptor proteins, mostly Fe transport.
 
  
 0.811
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolaseII, putative; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
   
 
 0.735
ISM_08625
Hypothetical protein.
  
 
 0.685
ISM_04230
Hemin degrading factor; COG3720 Putative heme degradation protein.
 
   
 0.673
Your Current Organism:
Roseovarius nubinhibens
NCBI taxonomy Id: 89187
Other names: R. nubinhibens ISM, Roseobacter sp. ISM, Roseovarius nubinhibens ISM, Roseovarius nubinhibens str. ISM, Roseovarius nubinhibens strain ISM, marine bacterium ISM
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